Across TCGA pan-cancer cohorts, CCDC75P1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of CCDC75P1’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CCDC75P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CCDC75P1 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
KIRC and THCA are the cancer types where CCDC75P1 tumor–normal differential expression is most reproducible.