Across TCGA patient cohorts, CCDC73 mutation is significantly associated with the total protein of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC73-associated genes across cancer lineages are ACC1, ASNS, and ATM. Each is linked with CCDC73 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC73-to-partner and partner-to-CCDC73 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC73→partner) and Y-score (partner→CCDC73) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ACC1 →	+0.621	+3.169	.001	.018	3	3
UCEC	ASNS →	+0.355	+1.263	.001	.019	3	3
UCEC	ATM →	-0.609	-1.947	<.001	<.001	3	3
LUAD	Bcl-2 →	-0.362	-3.305	.012	.010	3	2
SKCM	GAPDH →	+0.482	+2.321	.040	.033	3	2
SKCM	Ku80 →	+0.232	+3.169	.035	.017	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

Exploration

CCDC73 survival (RNA) · tumor vs normal (RNA) · all CCDC73 data types