Across TCGA cell cohorts, CCDC73 mutation is significantly associated with the RNA expression of many other genes, with 1,618 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC73-associated genes across cancer lineages are FMO1, ANKRD60, and LRIT1. Each is linked with CCDC73 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC73-to-partner and partner-to-CCDC73 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC73→partner) and Y-score (partner→CCDC73) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FMO1 →	+0.080	+1.970	<.001	.002	3	2
SKIN	ANKRD60 →	+0.008	+3.700	<.001	.009	3	1
SKIN	LRIT1 →	+0.010	+3.297	<.001	.002	3	1
SKIN	ODF1 →	+0.011	+3.700	<.001	.009	3	1
CNS	OR11H6 →	+0.026	+4.321	<.001	.009	3	1
CNS	HELT →	+0.027	+4.321	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,618 associations by consensus.

Exploration

CCDC73 survival (RNA) · tumor vs normal (RNA) · all CCDC73 data types