CCDC70

Across TCGA cell cohorts, CCDC70 RNA expression is significantly associated with the go_rna of many other GO terms, with 445 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CCDC70-associated GO terms across cancer lineages are Regulation of reproductive process, Regulation of meiotic cell cycle, and Cell cycle checkpoint signaling. Each is linked with CCDC70 in more than 3 cancer types. Because this analysis shows association rather than direction, both CCDC70-to-partner and partner-to-CCDC70 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of reproductive process grouped by CCDC70-low versus CCDC70-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC70→partner) and Y-score (partner→CCDC70) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Regulation of reproductive process →	+0.053	+0.027	.005	.001	3	4
KIDNEY	Regulation of meiotic cell cycle →	+0.067	+0.027	.008	.001	3	4
KIDNEY	Cell cycle checkpoint signaling →	+0.045	+0.023	.002	.006	3	4
LARGE_INTESTINE	Chaperone-mediated autophagy →	+0.083	+0.019	.002	.003	3	3
LARGE_INTESTINE	Regulation of protein exit from endoplasmic reticulum →	+0.057	+0.018	.005	.006	3	3
SOFT_TISSUE	Ventral spinal cord development →	-0.119	-0.011	.004	.009	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 445 associations by consensus.

Regulation of reproductive process by CCDC70 expression — KIDNEY

Explore this box plot interactively →