Across TCGA pan-cancer cohorts, CCDC7 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CCDC7 data layer compared with 23 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher CCDC7 Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated CCDC7 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC, COAD, and SKCM are the cancer types where CCDC7 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	II,III,IV	1.000	0.434	.009	26	view →
COAD	OS	Median	III,IV	0.157	0.791	.001	12	view →
SKCM	DFS	Median	III,IV	0.194	0.615	.024	6	view →
BRCA	DFS	Median	All	0.745	0.949	.048	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: CCDC7 tumor-vs-normal RNA expression · all CCDC7 data types