Across TCGA patient cohorts, CCDC69 mutation is significantly associated with the total protein of many other genes, with 47 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC69-associated genes across cancer lineages are Cyclin-B1, eEF2, and eIF4E. Each is linked with CCDC69 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC69-to-partner and partner-to-CCDC69 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC69→partner) and Y-score (partner→CCDC69) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-B1 →	+0.971	+3.000	<.001	.001	3	2
UCEC	eEF2 →	+0.466	+1.807	.001	.027	3	1
UCEC	eIF4E →	+0.222	+3.013	.010	.018	3	1
UCEC	A-Raf_pS299 →	-0.204	-3.321	<.001	.009	3	1
UCEC	FASN →	+0.495	+2.321	.002	.006	3	1
UCEC	FoxM1 →	+0.261	+2.321	.014	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 47 associations by consensus.

Exploration

CCDC69 survival (RNA) · tumor vs normal (RNA) · all CCDC69 data types