CCDC65

Across TCGA patient cohorts, CCDC65 mutation is significantly associated with the RNA expression of many other genes, with 386 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC65-associated genes across cancer lineages are RNA5SP419, TXN2, and CINP. Each is linked with CCDC65 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC65-to-partner and partner-to-CCDC65 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP419 grouped by CCDC65-low versus CCDC65-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC65→partner) and Y-score (partner→CCDC65) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP419 →	+0.572	+2.077	<.001	.003	3	3
UCEC	TXN2 →	+0.332	+2.184	.004	.002	3	2
UCEC	CINP →	+0.396	+3.301	<.001	<.001	3	2
UCEC	SDHB →	+0.436	+2.262	.001	.005	3	2
UCEC	RPS6KA1 →	+0.376	+2.617	.008	<.001	3	2
UCEC	BSPRY →	+0.698	+3.732	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 386 associations by consensus.

RNA5SP419 by CCDC65 expression — UCEC

Explore this box plot interactively →