CCDC65

Across TCGA cell cohorts, CCDC65 mutation is significantly associated with the RNA expression of many other genes, with 103 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC65-associated genes across cancer lineages are OR8B12, OR51J1, and OR2F1. Each is linked with CCDC65 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC65-to-partner and partner-to-CCDC65 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR8B12 grouped by CCDC65-low versus CCDC65-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC65→partner) and Y-score (partner→CCDC65) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	OR8B12 →	+0.061	+4.392	<.001	.003	3	1
OESOPHAGUS	OR51J1 →	+0.132	+4.017	<.001	.007	3	1
OESOPHAGUS	OR2F1 →	+0.016	+4.392	<.001	.003	3	1
OESOPHAGUS	OR8B3 →	+0.032	+4.392	<.001	.003	3	1
LARGE_INTESTINE	TTLL1 →	+0.731	+3.169	<.001	.009	3	1
LARGE_INTESTINE	RAB5IF →	-0.678	-3.416	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 103 associations by consensus.

OR8B12 by CCDC65 expression — OESOPHAGUS

Explore this box plot interactively →