CCDC61

Across TCGA pan-cancer cohorts, CCDC61 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CCDC61 data layer compared with 22 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CCDC61 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated CCDC61 expression acts as an unfavorable survival marker, although some lineages such as LUAD and CCRCC show a favorable association.

LUAD, UCEC, and HNSC are the cancer types where CCDC61 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Quartile	III,IV	0.747	0.271	.015	9	view →
UCEC	OS	Quartile	III,IV	0.349	1.000	.036	4	view →
HNSC	OS	Quartile	III,IV	0.736	0.976	.029	1	view →
CCRCC	OS	Quartile	All	0.858	0.598	.042	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CCDC61–LUAD (OS)

Open the LUAD breakdown →