CCDC61

Across TCGA patient cohorts, CCDC61 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,268 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CCDC61-associated proteins across cancer lineages are HDLBP, PAFAH1B3, and SPCS2. Each is linked with CCDC61 in more than 5 cancer types. Because this analysis shows association rather than direction, both CCDC61-to-partner and partner-to-CCDC61 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC61 versus HDLBP in GBM, with a Pearson correlation of -0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC61→partner) and Y-score (partner→CCDC61) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HDLBP →	-0.251	-0.387	.001	<.001	3	6
BRCA	PAFAH1B3 →	+0.385	+0.497	.002	.009	3	5
LSCC	SPCS2 →	-0.440	-0.312	<.001	<.001	3	4
LSCC	IRF2BP1 →	+0.309	+0.427	<.001	<.001	3	4
GBM	TAF4 →	+0.292	+0.398	.001	<.001	3	4
OV	HNRNPUL1 →	+0.322	+0.670	.008	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,268 associations by consensus.

CCDC61 vs HDLBP — GBM

Explore this scatter interactively →