CCDC61

Across TCGA patient cohorts, CCDC61 protein abundance is significantly associated with the RNA expression of many other genes, with 15,189 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCDC61-associated genes across cancer lineages are CD52, CASP12, and NCAPH. Each is linked with CCDC61 in more than 3 cancer types. Because this analysis shows association rather than direction, both CCDC61-to-partner and partner-to-CCDC61 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC61 versus CD52 in HNSC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC61→partner) and Y-score (partner→CCDC61) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CD52 →	+1.178	+0.339	<.001	<.001	3	4
LSCC	CASP12 →	+0.341	+0.252	<.001	<.001	3	4
BRCA	NCAPH →	-0.723	-0.311	.003	.001	3	4
LSCC	B3GNT4 →	-0.520	-0.322	.002	<.001	3	4
LSCC	EIF4G1 →	-0.657	-0.240	<.001	<.001	3	3
CCRCC	ATP13A3 →	-0.583	-0.180	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,189 associations by consensus.

CCDC61 vs CD52 — HNSC

Explore this scatter interactively →