CCDC61

Across TCGA cell cohorts, CCDC61 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CCDC61-associated genes across cancer lineages are SPIC and ADAM7. Each is linked with CCDC61 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC61-to-partner and partner-to-CCDC61 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPIC grouped by CCDC61-low versus CCDC61-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC61→partner) and Y-score (partner→CCDC61) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	SPIC →	+0.019	+5.415	<.001	.004	3	1
LARGE_INTESTINE	ADAM7 →	+0.007	+4.930	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

SPIC by CCDC61 expression — SKIN

Explore this box plot interactively →