CCDC60

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CCDC60 mutation is significantly associated with the total protein of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC60-associated genes across cancer lineages are INPP4B, MSH6, and S6_pS240_S244. Each is linked with CCDC60 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC60-to-partner and partner-to-CCDC60 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC60→partner) and Y-score (partner→CCDC60) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECINPP4B →-0.332-2.222.004.00932
UCECMSH6 →-0.411-2.000<.001.02932
UCECS6_pS240_S244 →+0.380+1.807.009.02532
UCECATM →-0.619-2.222<.001.01032
SKCMGATA6 →-0.191-2.292.013.02732
SKCMSmad1 →-0.109-2.000.012.02732
Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

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