CCDC6

Across TCGA patient cohorts, CCDC6 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,264 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCDC6-associated proteins across cancer lineages are CCDC6_S52, DDX50, and CCDC6_S244. Each is linked with CCDC6 in more than 6 cancer types. Because this analysis shows association rather than direction, both CCDC6-to-partner and partner-to-CCDC6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC6 versus CCDC6_S52 in LUAD, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC6→partner) and Y-score (partner→CCDC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CCDC6_S52 →	+0.644	+0.404	.001	<.001	3	7
LSCC	DDX50 →	+0.330	+0.473	<.001	<.001	3	6
UCEC	CCDC6_S244 →	+0.621	+0.832	<.001	<.001	3	6
CCRCC	PPA1 →	+0.300	+0.418	<.001	<.001	3	5
LSCC	SUPV3L1 →	+0.374	+0.396	<.001	<.001	3	5
PDAC	CCDC6_S367 →	+0.795	+0.419	.006	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,264 associations by consensus.

CCDC6 vs CCDC6_S52 — LUAD

Explore this scatter interactively →