CCDC6

Across TCGA cell cohorts, CCDC6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,856 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CCDC6-associated GO terms across cancer lineages are Positive regulation of mitochondrial ATP synthesis coupled electron transport, Cellular response to insulin stimulus, and Phosphatidylinositol-3-phosphate biosynthetic process. Each is linked with CCDC6 in more than 11 cancer types. Because this analysis shows association rather than direction, both CCDC6-to-partner and partner-to-CCDC6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mitochondrial ATP synthesis coupled electron transport grouped by CCDC6-low versus CCDC6-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC6→partner) and Y-score (partner→CCDC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of mitochondrial ATP synthesis coupled electron transport →	+0.093	+0.553	<.001	<.001	3	12
LUNG_SCLC	Cellular response to insulin stimulus →	+0.039	+0.545	<.001	.003	3	10
LARGE_INTESTINE	Phosphatidylinositol-3-phosphate biosynthetic process →	+0.044	+0.762	.001	.001	3	9
SOFT_TISSUE	Phosphatidylinositol phosphate biosynthetic process →	+0.041	+0.761	<.001	<.001	3	9
URINARY_TRACT	Inositol phosphate metabolic process →	+0.062	+0.696	.002	.002	3	8
BONE	Cellular response to calcium ion starvation →	+0.191	+0.686	.003	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,856 associations by consensus.

Positive regulation of mitochondrial ATP synthesis coupled electron transport by CCDC6 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →