CCDC59

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CCDC59 protein abundance is significantly associated with the RNA expression of many other genes, with 7,777 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCDC59-associated genes across cancer lineages are WDR43, RPL17, and ECT2. Each is linked with CCDC59 in more than 3 cancer types. Because this analysis shows association rather than direction, both CCDC59-to-partner and partner-to-CCDC59 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC59 versus WDR43 in UCEC, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC59→partner) and Y-score (partner→CCDC59) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECWDR43 →+0.789+0.494<.001<.00134
OVRPL17 →+0.619+0.371<.001.00224
LUADECT2 →+0.829+0.423.002.00133
UCECTEKT3 →-0.785-0.353<.001<.00133
UCECNAPSB →-1.656-0.341.001<.00133
UCECLRPPRC →+0.799+0.555<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,777 associations by consensus.

CCDC59 vs WDR43 — UCEC

Per-sample scatter of CCDC59 vs WDR43 in UCEC (Pearson r = 0.54).

Explore this scatter interactively →

Exploration