CCDC59

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CCDC59 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC59-associated genes across cancer lineages are SERPINA11. Each is linked with CCDC59 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC59-to-partner and partner-to-CCDC59 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SERPINA11 grouped by CCDC59-low versus CCDC59-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC59→partner) and Y-score (partner→CCDC59) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINESERPINA11 →+0.044+4.196.004.00231
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

SERPINA11 by CCDC59 expression — LARGE_INTESTINE

Box plot of SERPINA11 in CCDC59-low vs CCDC59-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration