Across TCGA pan-cancer cohorts, CCDC58P2 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of CCDC58P2’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CCDC58P2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CCDC58P2 is over-expressed in tumor, although a few such as KIRP show the opposite, repressed pattern.
KIRC and KIRP are the cancer types where CCDC58P2 tumor–normal differential expression is most reproducible.