CCDC58P1

Across TCGA pan-cancer cohorts, CCDC58P1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of CCDC58P1’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where CCDC58P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CCDC58P1 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

BRCA, LUSC, and STAD are the cancer types where CCDC58P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CCDC58P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	II,III,IV	+0.070	<.001	6	view →
LUSC	Female	All	+0.140	.001	5	view →
STAD	Female	III,IV	+0.195	<.001	2	view →
LIHC	Male	All	+0.068	.024	1	view →
THCA	Female	All	−0.054	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

CCDC58P1–BRCA

Open the BRCA breakdown →