CCDC58

Across TCGA patient cohorts, CCDC58 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,373 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCDC58-associated proteins across cancer lineages are UMPS, MCM4, and MCM5. Each is linked with CCDC58 in more than 8 cancer types. Because this analysis shows association rather than direction, both CCDC58-to-partner and partner-to-CCDC58 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC58 versus UMPS in LSCC, with a Pearson correlation of 0.73.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC58→partner) and Y-score (partner→CCDC58) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	UMPS →	+0.523	+1.005	<.001	<.001	3	9
OV	MCM4 →	+0.673	+0.509	<.001	.003	3	9
LUAD	MCM5 →	+0.618	+0.516	<.001	<.001	3	9
BRCA	TPX2 →	+0.744	+0.417	.001	.006	3	8
HNSC	TRIM28_S697 →	+0.910	+0.910	<.001	<.001	3	8
LSCC	DHX9 →	+0.264	+0.874	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,373 associations by consensus.

CCDC58 vs UMPS — LSCC

Explore this scatter interactively →