CCDC58

Across TCGA patient cohorts, CCDC58 protein abundance is significantly associated with the RNA expression of many other genes, with 14,068 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCDC58-associated genes across cancer lineages are FAM162A, UMPS, and MRPL3. Each is linked with CCDC58 in more than 6 cancer types. Because this analysis shows association rather than direction, both CCDC58-to-partner and partner-to-CCDC58 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC58 versus FAM162A in LSCC, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC58→partner) and Y-score (partner→CCDC58) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FAM162A →	+0.978	+0.445	<.001	<.001	3	7
LSCC	UMPS →	+0.780	+0.417	<.001	<.001	3	6
LSCC	MRPL3 →	+0.729	+0.460	<.001	<.001	3	6
UCEC	CNRIP1 →	-0.837	-0.364	.001	<.001	3	6
CCRCC	KLF2 →	-1.028	-0.379	<.001	<.001	3	6
UCEC	CLEC1A →	-0.688	-0.342	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,068 associations by consensus.

CCDC58 vs FAM162A — LSCC

Explore this scatter interactively →