CCDC58

Across TCGA cell cohorts, CCDC58 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,415 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible CCDC58-associated GO terms across cancer lineages are tRNA processing, tRNA wobble base modification, and RNA modification. Each is linked with CCDC58 in more than 17 cancer types. Because this analysis shows association rather than direction, both CCDC58-to-partner and partner-to-CCDC58 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA processing grouped by CCDC58-low versus CCDC58-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC58→partner) and Y-score (partner→CCDC58) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	tRNA processing →	+0.076	+0.942	.002	<.001	3	18
BONE	tRNA wobble base modification →	+0.076	+0.890	<.001	<.001	3	17
OVARY	RNA modification →	+0.059	+1.065	<.001	<.001	3	17
BONE	Mitochondrial gene expression →	+0.118	+0.834	.001	.009	3	16
BONE	tRNA 5'-leader removal →	+0.146	+1.031	<.001	.001	3	15
UPPER_AERODIGESTIVE_TRACT	Mitochondrial translation →	+0.102	+1.281	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,415 associations by consensus.

tRNA processing by CCDC58 expression — BONE

Explore this box plot interactively →