CCDC57

Across TCGA pan-cancer cohorts, CCDC57 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated CCDC57 data layer compared with 21 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher CCDC57 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CCDC57 expression acts as an unfavorable survival marker.

LUSC and STAD are the cancer types where CCDC57 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Median	All	0.150	0.724	.005	15	view →
STAD	OS	Median	III,IV	0.126	0.632	.001	12	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

CCDC57–LUSC (OS)

Open the LUSC breakdown →