CCDC57

Across TCGA patient cohorts, CCDC57 protein abundance is significantly associated with the RNA expression of many other genes, with 1,830 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CCDC57-associated genes across cancer lineages are UBXN10, ZNF474, and ERICH3. Each is linked with CCDC57 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC57-to-partner and partner-to-CCDC57 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC57 versus UBXN10 in UCEC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC57→partner) and Y-score (partner→CCDC57) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	UBXN10 →	+1.668	+0.716	<.001	<.001	3	3
UCEC	ZNF474 →	+1.329	+0.463	<.001	.008	3	3
UCEC	ERICH3 →	+1.982	+0.631	.001	<.001	3	3
LSCC	KRT23 →	+1.282	+0.279	.001	.006	3	2
UCEC	DNAH7 →	+1.815	+0.855	<.001	<.001	3	2
LUAD	CCDC170 →	+0.982	+0.371	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,830 associations by consensus.

CCDC57 vs UBXN10 — UCEC

Explore this scatter interactively →