CCDC57

Across TCGA cell cohorts, CCDC57 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,197 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CCDC57-associated GO terms across cancer lineages are Cilium-dependent cell motility, Sperm motility, and Cilium or flagellum-dependent cell motility. Each is linked with CCDC57 in more than 12 cancer types. Because this analysis shows association rather than direction, both CCDC57-to-partner and partner-to-CCDC57 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cilium-dependent cell motility grouped by CCDC57-low versus CCDC57-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC57→partner) and Y-score (partner→CCDC57) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.105	-0.957	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Sperm motility →	-0.115	-0.925	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.105	-0.957	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.115	-0.925	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.110	-0.957	<.001	<.001	3	13
SOFT_TISSUE	Microtubule nucleation →	+0.117	+1.452	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,197 associations by consensus.

Cilium-dependent cell motility by CCDC57 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →