CCDC51

Across TCGA pan-cancer cohorts, CCDC51 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated CCDC51 data layer compared with 21 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CCDC51 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CCDC51 expression acts as an unfavorable survival marker.

LUAD, THYM, and SKCM are the cancer types where CCDC51 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	II,III,IV	0.163	0.750	.001	24	view →
THYM	DFS	Median	All	0.123	0.871	<.001	12	view →
SKCM	OS	Median	III,IV	0.230	0.721	.004	10	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
LUSC	OS	Median	All	0.173	0.724	.012	6	view →
COAD	OS	Median	All	0.556	0.870	.008	6	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

CCDC51–LUAD (OS)

Open the LUAD breakdown →