CCDC50

Across TCGA cell cohorts, CCDC50 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,855 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CCDC50-associated GO terms across cancer lineages are Regulation of post-translational protein modification, Regulation of protein ubiquitination, and Regulation of extrinsic apoptotic signaling pathway via death domain receptors. Each is linked with CCDC50 in more than 11 cancer types. Because this analysis shows association rather than direction, both CCDC50-to-partner and partner-to-CCDC50 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of post-translational protein modification grouped by CCDC50-low versus CCDC50-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC50→partner) and Y-score (partner→CCDC50) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of post-translational protein modification →	+0.060	+0.847	<.001	<.001	3	12
OVARY	Regulation of protein ubiquitination →	+0.069	+1.168	<.001	<.001	3	11
BONE	Regulation of extrinsic apoptotic signaling pathway via death domain receptors →	+0.140	+1.013	<.001	<.001	3	11
SOFT_TISSUE	Positive regulation of protein ubiquitination →	+0.075	+1.212	<.001	<.001	3	11
OVARY	Positive regulation of post-translational protein modification →	+0.064	+1.029	<.001	<.001	3	10
OVARY	Regulation of protein modification by small protein conjugation or removal →	+0.062	+1.211	<.001	<.001	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,855 associations by consensus.

Regulation of post-translational protein modification by CCDC50 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →