CCDC42

Across TCGA cell cohorts, CCDC42 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC42-associated genes across cancer lineages are PTH and C10orf53. Each is linked with CCDC42 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC42-to-partner and partner-to-CCDC42 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PTH grouped by CCDC42-low versus CCDC42-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC42→partner) and Y-score (partner→CCDC42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PTH →	+0.049	+3.684	<.001	.006	3	1
LARGE_INTESTINE	C10orf53 →	+0.019	+4.217	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

PTH by CCDC42 expression — LARGE_INTESTINE

Explore this box plot interactively →