CCDC34

Across TCGA patient cohorts, CCDC34 protein abundance is significantly associated with the RNA expression of many other genes, with 2,056 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CCDC34-associated genes across cancer lineages are RPS3AP24, RPS2P48, and PVT1. Each is linked with CCDC34 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC34-to-partner and partner-to-CCDC34 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC34 versus RPS3AP24 in LUAD, with a Pearson correlation of 0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC34→partner) and Y-score (partner→CCDC34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RPS3AP24 →	+0.407	+0.693	.003	.001	3	2
LSCC	RPS2P48 →	-0.429	-1.023	.002	.009	3	2
LSCC	PVT1 →	-1.352	-0.792	.001	.001	3	2
LSCC	TMEM75 →	-1.743	-1.009	.008	.006	3	2
LUAD	MAPK1 →	+0.973	+0.676	.002	.004	3	1
LUAD	GRK3 →	+1.016	+0.518	.008	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,056 associations by consensus.

CCDC34 vs RPS3AP24 — LUAD

Explore this scatter interactively →