CCDC34

Across TCGA cell cohorts, CCDC34 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,894 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCDC34-associated GO terms across cancer lineages are Interstrand cross-link repair, DNA replication, and DNA-templated DNA replication. Each is linked with CCDC34 in more than 15 cancer types. Because this analysis shows association rather than direction, both CCDC34-to-partner and partner-to-CCDC34 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Interstrand cross-link repair grouped by CCDC34-low versus CCDC34-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC34→partner) and Y-score (partner→CCDC34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Interstrand cross-link repair →	+0.068	+0.906	.001	.002	3	16
OVARY	DNA replication →	+0.083	+0.986	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	DNA-templated DNA replication →	+0.106	+1.035	.005	.004	3	16
KIDNEY	Mitotic nuclear division →	+0.077	+1.132	.004	.003	3	16
BLOOD_Leukemia	Microtubule organizing center organization →	+0.055	+0.711	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Mitotic sister chromatid segregation →	+0.096	+0.947	.003	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,894 associations by consensus.

Interstrand cross-link repair by CCDC34 expression — OVARY

Explore this box plot interactively →