CCDC32

Across TCGA pan-cancer cohorts, CCDC32 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CCDC32 data layer compared with 28 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher CCDC32 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CCDC32 expression acts as an unfavorable survival marker.

KIRP, KIRC, and BLCA are the cancer types where CCDC32 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Median	All	0.199	0.903	<.001	15	view →
KIRC	OS	Median	All	0.167	0.655	.038	12	view →
BLCA	DFS	Median	All	0.174	0.625	.023	6	view →
SKCM	OS	Median	III,IV	0.233	0.705	.034	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CCDC32–KIRP (OS)

Open the KIRP breakdown →