CCDC32

Across TCGA patient cohorts, CCDC32 mutation is significantly associated with the RNA expression of many other genes, with 60 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible CCDC32-associated genes across cancer lineages are RN7SL591P, RNU4-79P, and RNU6-1216P. Each is linked with CCDC32 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC32-to-partner and partner-to-CCDC32 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL591P grouped by CCDC32-low versus CCDC32-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC32→partner) and Y-score (partner→CCDC32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RN7SL591P →	+0.237	+5.093	<.001	.008	3	2
BLCA	RNU4-79P →	+0.208	+7.640	<.001	.009	3	2
SKCM	RNU6-1216P →	+0.415	+5.118	<.001	.001	3	1
SKCM	RNA5SP378 →	+0.512	+5.254	<.001	.001	3	1
SKCM	RNA5SP192 →	+0.253	+6.485	<.001	<.001	3	1
SKCM	RNU6-522P →	+0.289	+4.970	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 60 associations by consensus.

RN7SL591P by CCDC32 expression — LUSC

Explore this box plot interactively →