CCDC30

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CCDC30 mutation is significantly associated with the total protein of many other genes, with 43 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC30-associated genes across cancer lineages are Caspase-7-cleavedD198, mTOR_pS2448, and Notch1. Each is linked with CCDC30 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC30-to-partner and partner-to-CCDC30 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC30→partner) and Y-score (partner→CCDC30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCaspase-7-cleavedD198 →+0.557+2.926.006<.00133
UCECmTOR_pS2448 →-0.115-1.565.026.03432
UCECNotch1 →+0.175+2.232<.001.00532
SKCMp62 Lck ligand →+0.424+2.820.014.03532
UCECCaspase-8 →-0.235-2.476.006.00132
UCECC-Raf →+0.163+1.584.001.03432
Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

Exploration