Across TCGA cell cohorts, CCDC30 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC30-associated genes across cancer lineages are GH1, APOL4, and OR10R2. Each is linked with CCDC30 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC30-to-partner and partner-to-CCDC30 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC30→partner) and Y-score (partner→CCDC30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	GH1 →	+0.047	+4.212	.001	.007	3	1
LARGE_INTESTINE	APOL4 →	+0.675	+3.369	<.001	.005	3	1
LARGE_INTESTINE	OR10R2 →	+0.021	+2.977	<.001	.006	3	1
LARGE_INTESTINE	KLHL23 →	+0.762	+3.192	.002	.007	3	1
LARGE_INTESTINE	RSC1A1 →	+0.739	+3.478	.005	.002	3	1
LARGE_INTESTINE	SMIM33 →	+0.564	+2.648	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

CCDC30 survival (RNA) · tumor vs normal (RNA) · all CCDC30 data types