CCDC28B

Across TCGA pan-cancer cohorts, CCDC28B Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CCDC28B data layer compared with 25 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in kidney chromophobe (KICH), where higher CCDC28B Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated CCDC28B expression acts as an unfavorable survival marker.

KICH, UCEC, and COAD are the cancer types where CCDC28B Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Median	All	0.102	0.848	.004	13	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
COAD	OS	Median	III,IV	0.168	0.692	.043	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

CCDC28B–KICH (DFS)

Open the KICH breakdown →