CCDC28A

Across TCGA pan-cancer cohorts, CCDC28A mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated CCDC28A data layer compared with 26 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CCDC28A mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated CCDC28A expression acts as an unfavorable survival marker, although some lineages such as CCRCC and PDAC show a favorable association.

CCRCC, LUAD, and PDAC are the cancer types where CCDC28A mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	IV	1.000	0.451	.016	17	view →
LUAD	DFS	Quartile	III,IV	0.463	0.995	.006	15	view →
PDAC	OS	Median	II,III,IV	0.968	0.697	.012	10	view →
UCEC	DFS	Median	All	0.946	0.866	.041	2	view →
HNSC	OS	Quartile	All	0.641	0.841	.033	1	view →
GBM	OS	Quartile	All	0.695	0.860	.041	1	view →
LSCC	DFS	Median	III,IV	0.471	0.837	.029	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

CCDC28A–CCRCC (OS)

Open the CCRCC breakdown →