CCDC28A

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CCDC28A protein abundance is significantly associated with the RNA expression of many other genes, with 13,762 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CCDC28A-associated genes across cancer lineages are NCAPH, ESPL1, and SAMD1. Each is linked with CCDC28A in more than 5 cancer types. Because this analysis shows association rather than direction, both CCDC28A-to-partner and partner-to-CCDC28A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC28A versus NCAPH in UCEC, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC28A→partner) and Y-score (partner→CCDC28A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECNCAPH →-1.019-0.312<.001<.00136
UCECESPL1 →-1.083-0.251<.001<.00136
BRCASAMD1 →-0.610-0.289<.001<.00136
BRCAPLK1 →-0.703-0.295.009.00136
UCECCDKN3 →-1.011-0.236<.001.00735
UCECCENPI →-1.000-0.314<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,762 associations by consensus.

CCDC28A vs NCAPH — UCEC

Per-sample scatter of CCDC28A vs NCAPH in UCEC (Pearson r = -0.40).

Explore this scatter interactively →

Exploration