CCDC28A

Across TCGA patient cohorts, CCDC28A mutation is significantly associated with the RNA expression of many other genes, with 849 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC28A-associated genes across cancer lineages are MTND6P17, BTF3L4P4, and MIR4695. Each is linked with CCDC28A in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC28A-to-partner and partner-to-CCDC28A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTND6P17 grouped by CCDC28A-low versus CCDC28A-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC28A→partner) and Y-score (partner→CCDC28A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	MTND6P17 →	+0.103	+7.924	<.001	.008	3	3
BLCA	BTF3L4P4 →	+0.042	+4.296	<.001	.006	3	2
BLCA	MIR4695 →	+0.173	+4.122	<.001	.008	3	2
SKCM	FTLP1 →	+0.091	+2.080	.008	.008	3	2
SKCM	RPS12P15 →	+0.056	+2.714	.002	<.001	3	2
SKCM	RPL12P21 →	+0.087	+2.005	.007	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 849 associations by consensus.

MTND6P17 by CCDC28A expression — LUSC

Explore this box plot interactively →