CCDC28A

Across TCGA cell cohorts, CCDC28A RNA expression is significantly associated with the go_rna of many other GO terms, with 2,767 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CCDC28A-associated GO terms across cancer lineages are Regulation of autophagosome assembly, Autophagy of peroxisome, and Pexophagy. Each is linked with CCDC28A in more than 12 cancer types. Because this analysis shows association rather than direction, both CCDC28A-to-partner and partner-to-CCDC28A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of autophagosome assembly grouped by CCDC28A-low versus CCDC28A-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC28A→partner) and Y-score (partner→CCDC28A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Regulation of autophagosome assembly →	+0.095	+1.181	<.001	<.001	3	13
OVARY	Autophagy of peroxisome →	+0.076	+0.831	<.001	.001	3	11
OVARY	Pexophagy →	+0.076	+0.831	<.001	.001	3	11
OESOPHAGUS	1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process →	+0.088	+0.776	<.001	.005	2	11
LUNG_NSCLC_LUSC	7-methylguanosine RNA capping →	+0.122	+0.870	<.001	<.001	3	10
CNS	RNA polymerase II preinitiation complex assembly →	+0.063	+0.680	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,767 associations by consensus.

Regulation of autophagosome assembly by CCDC28A expression — BLOOD_Myeloma

Explore this box plot interactively →