CCDC28A

Across TCGA cell cohorts, CCDC28A mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC28A-associated genes across cancer lineages are OR2H1, HHLA1, and TAC4. Each is linked with CCDC28A in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC28A-to-partner and partner-to-CCDC28A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2H1 grouped by CCDC28A-low versus CCDC28A-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC28A→partner) and Y-score (partner→CCDC28A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	OR2H1 →	+0.027	+4.029	<.001	.009	3	1
LARGE_INTESTINE	HHLA1 →	+0.529	+3.584	<.001	.006	3	1
LARGE_INTESTINE	TAC4 →	+0.181	+3.626	.002	.003	3	1
LARGE_INTESTINE	ELOA3DP →	+0.026	+2.688	<.001	.008	3	1
LARGE_INTESTINE	PHF24 →	+0.082	+3.321	.004	.009	2	1
LARGE_INTESTINE	MSH4 →	+0.311	+3.464	<.001	.004	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

OR2H1 by CCDC28A expression — OVARY

Explore this box plot interactively →