CCDC28A

Across TCGA cell cohorts, CCDC28A mutation is significantly associated with the mutation status of many other genes, with 1,841 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC28A-associated genes across cancer lineages are MOSPD3, SLC5A7, and RCOR3. Each is linked with CCDC28A in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC28A-to-partner and partner-to-CCDC28A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MOSPD3 grouped by CCDC28A-low versus CCDC28A-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC28A→partner) and Y-score (partner→CCDC28A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	MOSPD3 →	+6.014	+6.014	.001	.001	1	3
BLOOD_Lymphoma	SLC5A7 →	+6.014	+6.014	.001	.001	1	3
BLOOD_Lymphoma	RCOR3 →	+6.014	+6.014	.001	.001	1	3
BLOOD_Lymphoma	USP35 →	+6.014	+6.014	.001	.001	1	3
BLOOD_Lymphoma	PLCG1 →	+4.014	+4.969	.008	.008	1	3
BLOOD_Lymphoma	IQSEC2 →	+4.014	+4.969	.008	.008	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,841 associations by consensus.

MOSPD3 by CCDC28A expression — BLOOD_Lymphoma

Explore this box plot interactively →