CCDC25

Across TCGA patient cohorts, CCDC25 protein abundance is significantly associated with the RNA expression of many other genes, with 5,646 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CCDC25-associated genes across cancer lineages are INTS10, MCPH1, and INTS9. Each is linked with CCDC25 in more than 8 cancer types. Because this analysis shows association rather than direction, both CCDC25-to-partner and partner-to-CCDC25 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC25 versus INTS10 in UCEC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC25→partner) and Y-score (partner→CCDC25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	INTS10 →	+0.589	+0.291	.002	.001	3	9
OV	MCPH1 →	+0.667	+0.402	<.001	.001	3	9
OV	INTS9 →	+0.856	+0.447	<.001	<.001	3	8
UCEC	R3HCC1 →	+0.765	+0.249	.005	.002	3	8
BRCA	SARAF →	+0.670	+0.266	<.001	<.001	3	8
UCEC	ELP3 →	+1.111	+0.312	.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,646 associations by consensus.

CCDC25 vs INTS10 — UCEC

Explore this scatter interactively →