CCDC25

Across TCGA patient cohorts, CCDC25 mutation is significantly associated with the RNA expression of many other genes, with 2,488 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC25-associated genes across cancer lineages are LSM3P2, PMM2P2, and MIR8058. Each is linked with CCDC25 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC25-to-partner and partner-to-CCDC25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LSM3P2 grouped by CCDC25-low versus CCDC25-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC25→partner) and Y-score (partner→CCDC25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	LSM3P2 →	+0.232	+4.563	<.001	.004	3	2
SKCM	PMM2P2 →	+0.073	+4.771	<.001	.006	3	2
COAD	MIR8058 →	+1.167	+4.289	<.001	.003	3	2
UCEC	RPL31P54 →	+0.132	+2.835	.001	.003	3	2
UCEC	PSMD12P1 →	+0.148	+2.914	.002	.001	3	2
UCEC	VDAC3P1 →	+0.254	+2.850	.009	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,488 associations by consensus.

LSM3P2 by CCDC25 expression — SKCM

Explore this box plot interactively →