CCDC25

Across TCGA cell cohorts, CCDC25 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,155 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCDC25-associated GO terms across cancer lineages are Regulation of regulatory ncRNA-mediated heterochromatin formation, Negative regulation of regulatory ncRNA-mediated heterochromatin formation, and Protein acetylation. Each is linked with CCDC25 in more than 11 cancer types. Because this analysis shows association rather than direction, both CCDC25-to-partner and partner-to-CCDC25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of regulatory ncRNA-mediated heterochromatin formation grouped by CCDC25-low versus CCDC25-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC25→partner) and Y-score (partner→CCDC25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of regulatory ncRNA-mediated heterochromatin formation →	+0.128	+0.792	<.001	<.001	3	12
PANCREAS	Negative regulation of regulatory ncRNA-mediated heterochromatin formation →	+0.128	+0.792	<.001	<.001	3	12
BONE	Protein acetylation →	+0.064	+0.724	.003	.001	3	11
SOFT_TISSUE	Negative regulation of sister chromatid cohesion →	+0.126	+0.685	<.001	<.001	2	11
URINARY_TRACT	Mismatch repair →	+0.073	+0.986	<.001	<.001	3	10
LARGE_INTESTINE	snRNA metabolic process →	+0.059	+0.842	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,155 associations by consensus.

Regulation of regulatory ncRNA-mediated heterochromatin formation by CCDC25 expression — PANCREAS

Explore this box plot interactively →