CCDC22

Across TCGA patient cohorts, CCDC22 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,178 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCDC22-associated proteins across cancer lineages are GPKOW, PHPT1, and HSD17B10. Each is linked with CCDC22 in more than 4 cancer types. Because this analysis shows association rather than direction, both CCDC22-to-partner and partner-to-CCDC22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC22 versus GPKOW in OV, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC22→partner) and Y-score (partner→CCDC22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	GPKOW →	+0.287	+0.613	.001	<.001	3	5
GBM	PHPT1 →	-0.316	-0.365	<.001	<.001	3	4
COAD	HSD17B10 →	+0.327	+0.426	<.001	<.001	3	4
OV	HUWE1 →	+0.277	+0.539	<.001	.001	2	5
COAD	NOP10 →	+0.285	+0.418	.001	.003	3	4
OV	PDK3 →	+0.441	+0.482	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,178 associations by consensus.

CCDC22 vs GPKOW — OV

Explore this scatter interactively →