CCDC200

Across TCGA pan-cancer cohorts, CCDC200 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated CCDC200 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher CCDC200 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CCDC200 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCS show a favorable association.

UVM, HNSC, and LGG are the cancer types where CCDC200 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Tertile	All	0.367	0.786	<.001	117	view →
HNSC	DFS	Tertile	II,III,IV	0.370	0.267	.003	74	view →
LGG	DFS	Median	All	0.631	0.831	<.001	49	view →
UCS	DFS	Median	IV	0.885	0.440	.015	40	view →
UCEC	OS	Median	IV	0.689	0.240	.001	36	view →
COAD	OS	Median	All	0.515	0.689	.005	28	view →
LUSC	DFS	Median	II,III,IV	0.649	0.776	.003	25	view →
MESO	DFS	Quartile	All	0.319	0.780	.006	24	view →
ACC	DFS	Tertile	III,IV	0.114	0.672	.002	24	view →
SKCM	OS	Tertile	All	0.404	0.261	.010	19	view →
LIHC	OS	Quartile	II,III,IV	0.491	0.792	.003	17	view →
LUAD	OS	Median	II,III,IV	0.566	0.344	.001	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

CCDC200–UVM (DFS)

Open the UVM breakdown →