CCDC198

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CCDC198 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CCDC198 data layer compared with 21 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher CCDC198 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CCDC198 expression acts as an unfavorable survival marker.

BLCA, LIHC, and STAD are the cancer types where CCDC198 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BLCAOSMedianIV0.0900.605<.00112view →
LIHCDFSMedianAll0.0440.553<.00112view →
STADOSMedianIII,IV0.1840.641.0116view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

CCDC198–BLCA (OS)

Kaplan–Meier survival curve for CCDC198 mutant vs wild-type samples in BLCA.

Open the BLCA breakdown →

Exploration