CCDC198

Across TCGA patient cohorts, CCDC198 mutation is significantly associated with the RNA expression of many other genes, with 295 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC198-associated genes across cancer lineages are RN7SKP221, RNU6-454P, and RNA5SP84. Each is linked with CCDC198 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC198-to-partner and partner-to-CCDC198 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP221 grouped by CCDC198-low versus CCDC198-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC198→partner) and Y-score (partner→CCDC198) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RN7SKP221 →	+0.065	+7.471	<.001	.008	3	2
BLCA	RNU6-454P →	+0.266	+5.444	<.001	.002	3	2
BLCA	RNA5SP84 →	+0.315	+6.307	<.001	<.001	3	2
BLCA	RNU6-715P →	+0.295	+6.040	<.001	.001	3	2
UCEC	MIR4710 →	+0.620	+3.031	<.001	.003	3	2
UCEC	PI4K2A →	+0.440	+3.459	.004	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 295 associations by consensus.

RN7SKP221 by CCDC198 expression — BRCA

Explore this box plot interactively →