CCDC198

Across TCGA cell cohorts, CCDC198 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC198-associated genes across cancer lineages are TSPAN16, ZIC3, and TAS2R7. Each is linked with CCDC198 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC198-to-partner and partner-to-CCDC198 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TSPAN16 grouped by CCDC198-low versus CCDC198-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC198→partner) and Y-score (partner→CCDC198) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	TSPAN16 →	+0.042	+4.017	<.001	.007	3	1
OESOPHAGUS	ZIC3 →	+0.704	+4.392	<.001	.003	3	1
LARGE_INTESTINE	TAS2R7 →	+0.010	+3.700	<.001	.009	3	1
LARGE_INTESTINE	BRDT →	+0.111	+3.333	<.001	.009	3	1
LARGE_INTESTINE	CCDC54 →	+0.145	+3.736	<.001	.004	3	1
LARGE_INTESTINE	LCE1D →	+0.236	+3.217	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

TSPAN16 by CCDC198 expression — OESOPHAGUS

Explore this box plot interactively →