Across TCGA patient cohorts, CCDC189 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,165 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible CCDC189-associated GO terms across cancer lineages are Axoneme assembly, Motile cilium assembly, and Mitotic intra-S DNA damage checkpoint signaling. Each is linked with CCDC189 in more than 26 cancer types. Because this analysis shows association rather than direction, both CCDC189-to-partner and partner-to-CCDC189 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC189→partner) and Y-score (partner→CCDC189) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Axoneme assembly →	+0.091	+0.810	<.001	<.001	3	27
UCEC	Motile cilium assembly →	+0.063	+0.785	<.001	<.001	3	27
SCLC	Mitotic intra-S DNA damage checkpoint signaling →	+0.107	+0.920	<.001	<.001	3	26
UCEC	Axonemal dynein complex assembly →	+0.105	+0.784	<.001	<.001	3	25
SCLC	Positive regulation of cilium assembly →	+0.113	+1.093	<.001	<.001	3	24
BRCA	Methylglyoxal metabolic process →	+0.056	+0.692	<.001	<.001	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,165 associations by consensus.

Exploration

CCDC189 survival (RNA) · tumor vs normal (RNA) · all CCDC189 data types